IL-4 Antikörper

Produktnummer ABIN7670095

Der Maus Monoklonal Anti-IL-4-Antikörper wurde für FACS validiert. Er ist geeignet, IL-4 in Proben von Ratte zu detektieren.

Kurzübersicht für IL-4 Antikörper (ABIN7670095)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 5B3

Produktdetails anti-IL-4 Antikörper

Verwendungszweck: Purified Anti-Rat IL4 Antibody[5B3]

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Andere Bezeichnung: IL4

Hintergrund: Interleukin,B-cell growth factor,B-cell stimulatory factor,Lymphocyte stimulatory factor,BCGF1,B-cell IGG differentiation factor,B-cell stimulatory factor 1,BCGF-1,Binetrakin,BSF1,Interleukin-4,Lymphocyte stimulatory factor 1,Pitrakinra,Il4,BSF-1,Lymphocy,Il 4,B-cell growth factor 1,Il-4,IL4, BCGF-1, BCGF1, BSF-1, BSF1,IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells and basophils. IL-4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

UniProt: P20096

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation