PSMA Antikörper

Produktnummer ABIN8062755

Der Maus Monoklonal anti-PSMA Antikörper wird verwendet zum Nachweis von PSMA in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für PSMA Antikörper (ABIN8062755)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PSMA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 107-1A4

Produktdetails anti-PSMA Antikörper

Verwendungszweck: Purified Anti-Human FOLH1 Antibody[107-1A4]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Andere Bezeichnung: FOLH1

Hintergrund: GCP,GIG,Folate hydrolase,Glutamate carboxypeptidase,NAALAD,FGCP,FOLH,GCP2,GCPII,NAALAD1,NAALAdase,PSM,PSMA,mGCP,FOLH1,Cell growth-inhibiting gene 27 protein,Folate hydrolase 1,Glutamate carboxypeptidase 2,NAALADase I,N-acetylated alpha-linked acidic dipeptidase 1|cell growth-inhibiting protein 27|folate hydrolase 1|folylpoly-gamma-glutamate carboxypep,GIG27,FGCP,FOLH,GCP2,GCPII,NAALAD1,NAALAdase,PSM,PSMA,mGCP,FOLH1,This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]

UniProt: Q04609