CD80 Antikörper
Kurzübersicht für CD80 Antikörper (ABIN7670033)
Target
Alle CD80 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Purified Anti-Human CD80 Antibody[2F4]
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- ≥ 1 mg/mL
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Buffer
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- avoid freeze / thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- CD80
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Andere Bezeichnung
- CD80
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Hintergrund
- LAB,CTLA-4 counter-receptor B,T-lymphocyte activation antigen CD,B7,B7-1,B7.1,BB1,CD28LG,CD28LG1,LAB7,CD80,CD28LGB7-1 antigen,T-lymphocyte activation antigen CD80,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1, B7-1, BB1,B lymphocyte activation antigen B7,B7-1 antigen,B7-1 antigen),CD28 antigen ligand 1,CD80 antigen,CD80 antigen (CD28 antigen ligand 1,CD80 Molecule,Costimulatory factor CD80,costimulatory molecule variant IgV-CD80,B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.
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UniProt
- P33681
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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