CD276 Antikörper

Produktnummer ABIN7670004

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD276 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD276 Antikörper (ABIN7670004)

Target: CD276

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 6A1

Produktdetails anti-CD276 Antikörper

Verwendungszweck: Purified Anti-Human CD276 Antibody[6A1]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD276

Target: CD276

Andere Bezeichnung: CD276

Hintergrund: B7H;UNQ;PRO;B7-H;B7RP;B7 homolog;B7H34Ig-B7-H;PSEC;4Ig-B7-H;CD276;4Ig-B7-H3;B7-H3;B7H3;B7RP-2;B7 homolog 3;B7H34Ig-B7-H3;CD276 antigen;CD276 molecule;Costimulatory molecule;PSEC0249;UNQ309;PRO352; B7RP-2;4Ig-B7-H3;B7H3;B7-H3;CD276 antigen,The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints