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CD45RO Antikörper

Der Kaninchen Polyklonal Anti-CD45RO-Antikörper wurde für IHC (p), WB und IF (p) validiert. Er ist geeignet, CD45RO in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN733283

Kurzübersicht für CD45RO Antikörper (ABIN733283)

Target

CD45RO

Reaktivität

  • 70
  • 13
  • 13
  • 11
  • 11
  • 2
  • 2
Human, Maus, Ratte

Wirt

  • 60
  • 12
Kaninchen

Klonalität

  • 61
  • 11
Polyklonal

Konjugat

  • 15
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD45RO Antikörper ist unkonjugiert

Applikation

  • 55
  • 29
  • 22
  • 13
  • 12
  • 12
  • 11
  • 10
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human

    Aufreinigung

    Purified by Protein A.

    Immunogen

    Cultured T cells from human IL-2-dependent T-cell line (CA1) prepared from human peripheral blood activated with influenza virus.

    Isotyp

    IgG
  • Applikationshinweise

    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    CD45RO

    Andere Bezeichnung

    CD45RO

    Hintergrund

    Synonyms: B220, CD 45, CD45, cd45 antigen, ec3.1.3.48, CD45R, GP180, GP180, GP 180, L CA, LCA, L-CA, Leukocyte common antigen, LY5, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, Receptor-type tyrosine-protein phosphatase C, PTPRC, PTPRC_HUMAN, SCID due to PTPRC deficiency, T200, T200 glycoprotein, T200 leukocyte common antigen, Human homolog of severe combined immunodeficiency due to PTPRC deficiency.

    Background: CD45RO is a single chain transmembraneous glycoprotein which represents the low molecular weight isoform of the Leucocyte Common Antigen (LCA). It is expressed on most thymocytes, about 45 % of peripheral blood T cells, virtually all T cells in skin reactive infiltrates, and the majority of T cell malignancies. It is also found on a subset of B cells and on exceptional B cell lymphomas.CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.

    Molekulargewicht

    180kDa

    Gen-ID

    5788
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