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CD45RO Antikörper

CD45RO Reaktivität: Human WB, IHC, IF (p), ICC, mIF Wirt: Maus Monoclonal UCHL-1 unconjugated

Produktnummer ABIN7449553

Datenblatt (PDF)

Target Alle CD45RO Produkte

CD45RO
Reaktivität
75

12

12

11

11
Human
Wirt
63

12
Maus
Passende Sekundärantikörper
Klonalität
63

12
Monoklonal
Konjugat
11

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD45RO Antikörper ist unkonjugiert
Applikation
58

29

25

13

12

10

10

9

4

3

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)

Verwendungszweck

Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]

Immunogen

Cultured T-cells from an IL-2-dependent T-cell line (CA1)

Klon

UCHL-1

Isotyp

IgG
anti-CD45RO (CD45RO) antibody
CD45RO Reaktivität: Human, Maus, Ratte WB, IHC (p), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD45RO (CD45RO) antibody
GMP Grade CD45RO Reaktivität: Human FACS, IHC, IP Wirt: Maus Monoclonal UCHL1 unconjugated

anti-CD45RO (CD45RO) antibody (FITC)
GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 FITC

anti-CD45RO (CD45RO) antibody (PE)
GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 PE

anti-CD45RO (CD45RO) antibody (mFluor™450)
GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 mFluor™450

anti-CD45RO (CD45RO) antibody (APC)
GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 APC

anti-CD45RO (CD45RO) antibody (PE-CF®594)
GMP Grade CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 PE-CF®594

anti-CD45RO (CD45RO) antibody (PE-Cy7)
CD45RO Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal UCHL1 PE-Cy7

anti-CD45RO (CD45RO) antibody
CD45RO Reaktivität: Human, Schimpanse, Marmoset FACS, IF, IHC (p) Wirt: Maus Monoclonal UCHL-1 unconjugated

anti-CD45RO (CD45RO) antibody (FITC)
CD45RO Reaktivität: Human FACS Wirt: Maus Monoclonal UCHL1 FITC

Applikationshinweise

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 05:10:00

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

50 μg/mL

Buffer

Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Haltbarkeit

12 months
Target

CD45RO

Andere Bezeichnung

CD45RO (CD45RO Produkte)

Hintergrund

Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].

Gen-ID

5788

NCBI Accession

NP_002829

UniProt

P08575