Rekombinanter YBX1 Antikörper (CF®647)

Produktnummer ABIN7662068

Der Maus Monoklonal Anti-YBX1-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, YBX1 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter YBX1 Antikörper (CF®647) (ABIN7662068)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YBX1 Antikörper ist konjugiert mit CF®647

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: RYBX1-2430

Produktdetails anti-YBX1 Antikörper (CF®647)

Verwendungszweck: YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)(rYBX1/2430), CF647 conjugate

Produktmerkmale: The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19,000 full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human full-length YBX1 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Andere Bezeichnung: Y-box Binding Protein 1

Hintergrund:

Synonyms: BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1

Gene Symbol: YBX1

Molekulargewicht: 36 kDa

Gen-ID: 4904

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation