UPK1A Antikörper (AA 114-173) (CF®568)

Produktnummer ABIN7661630

Der Maus Monoklonal Anti-UPK1A-Antikörper wurde für validiert. Er ist geeignet, UPK1A in Proben von Human zu detektieren.

Kurzübersicht für UPK1A Antikörper (AA 114-173) (CF®568) (ABIN7661630)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UPK1A Antikörper ist konjugiert mit CF®568

Applikation: Bitte anfragen

Klon: UPK1A-2923

Produktdetails anti-UPK1A Antikörper (CF®568)

Bindungsspezifität: AA 114-173

Verwendungszweck: Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2923), CF568 conjugate

Produktmerkmale: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: Urinary Bladder.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Andere Bezeichnung: Uroplakin 1A

Hintergrund:

Synonyms: UP1A, UPIA, UPKA, TSPAN21

Gene Symbol: UPK1A

Molekulargewicht: 29 kDa

Gen-ID: 11045

UniProt: O00322