UPK1A Antikörper (AA 114-173) (CF®405S)

Produktnummer ABIN7661617

Dieses Maus Monoklonal-Antikörper erkennt spezifisch UPK1A in IHC und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UPK1A Antikörper (AA 114-173) (CF®405S) (ABIN7661617)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UPK1A Antikörper ist konjugiert mit CF®405S

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: UPK1A-2925

Produktdetails anti-UPK1A Antikörper (CF®405S)

Bindungsspezifität: AA 114-173

Verwendungszweck: Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2925), CF405S conjugate

Produktmerkmale: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: Urinary Bladder.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Andere Bezeichnung: Uroplakin 1A

Hintergrund:

Synonyms: UP1A, UPIA, UPKA, TSPAN21

Gene Symbol: UPK1A

Molekulargewicht: 29 kDa

Gen-ID: 11045

UniProt: O00322