UGT1A9 Antikörper (CF®740)

Produktnummer ABIN7661612

Der Maus Monoklonal Anti-UGT1A9-Antikörper wurde für validiert. Er ist geeignet, UGT1A9 in Proben von Human zu detektieren.

Kurzübersicht für UGT1A9 Antikörper (CF®740) (ABIN7661612)

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UGT1A9 Antikörper ist konjugiert mit CF®740

Applikation: Bitte anfragen

Klon: UGT1A9-1229

Produktdetails anti-UGT1A9 Antikörper (CF®740)

Verwendungszweck: UGT1A9 (UDP glucuronosyltransferase 1 family, polypeptide A9)(UGT1A9/1229), CF740 conjugate

Produktmerkmale: This antibody recognizes a protein of about 60 kDa, which is identified as human UGT1A9. It does not cross-react with the other UGT1A isoforms including UGT1A7, UGT1A8, and UGT1A10 and shows a high degree of specificity. UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This MAb binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC s). In frozen sections, it stains hepatic cells and may be used as a marker of the liver. This MAb also binds to cell preparations of hepatocellular carcinoma biopsies or cell lines.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A synthetic peptide specific to human UGT1A9 protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: HepG2 cells. Liver or Hepatocellular Carcinoma (HCC)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu UGT1A9

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Andere Bezeichnung: UGT1A9

Hintergrund:

Synonyms: GNT1, HLUGP4, lugP4, UDP-glucuronosyltransferase 1-I, UDP-glucuronosyltransferase 1A9 (UGT1A9), UDPGT 1-9, UDPGT, UGT-1I, UGT1*9, UGT1-09, UGT1.9, Ugt1a9, UGT1I

Gene Symbol: UGT1A9

Molekulargewicht: 60 kDa

Gen-ID: 54600

UniProt: O60656

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha