UGT1A9 Antikörper (AA 26-250)

Produktnummer ABIN3022343

Der Kaninchen Polyklonal anti-UGT1A9 Antikörper (ABIN3022343) detektiert spezifisch UGT1A9 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für UGT1A9 Antikörper (AA 26-250) (ABIN3022343)

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-UGT1A9 Antikörper

Bindungsspezifität: AA 26-250

Sequenz: GKLLVVPMDG SHWFTMRSVV EKLILRGHEV VVVMPEVSWQ LGRSLNCTVK TYSTSYTLED LDREFKAFAH AQWKAQVRSI YSLLMGSYND IFDLFFSNCR SLFKDKKLVE YLKESSFDAV FLDPFDNCGL IVAKYFSLPS VVFARGILCH YLEEGAQCPA PLSYVPRILL GFSDAMTFKE RVRNHIMHLE EHLLCHRFFK NALEIASEIL QTPVTEYDLY SHTSI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-250 of human UGT1A9 (NP_066307.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UGT1A9

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Andere Bezeichnung: UGT1A9

Hintergrund: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.,UGT1A9,HLUGP4,LUGP4,UDPGT,UDPGT 1-9,UGT-1I,UGT1-09,UGT1-9,UGT1.9,UGT1A9S,UGT1AI,UGT1I,UDPGT1-9,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Drug metabolism,UGT1A9

Molekulargewicht: 49 kDa/59 kDa

Gen-ID: 54600

UniProt: O60656

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha