SULT1E1 Antikörper (CF®405S)
Kurzübersicht für SULT1E1 Antikörper (CF®405S) (ABIN7660464)
Target
Alle SULT1E1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Sulfotransferase family 1E, estrogen-preferring, member 1(CPTC-SULT1E1-1), CF405S conjugate
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Produktmerkmale
- The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant full-length human SULT1E1 protein
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Positive Control: HEP G2, liver, intestine and kidney.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
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Andere Bezeichnung
- Sulfotransferase family 1E, estrogen-preferring, member 1
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Hintergrund
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Synonyms: EST, EST-1, EST1, Estrogen sulfotransferase, estrogen-preferring, estrone sulfotransferase, ST1E1, STE, Sulfotransferase 1E1, Sulfotransferase , Sulfotransferase estrogen preferring
Gene Symbol: SULT1E1
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Molekulargewicht
- 35 kDa
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Gen-ID
- 6783
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UniProt
- P49888
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Pathways
- Steroid Hormone Biosynthesis
Target
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