SPTBN1 Antikörper (CF®594)

Produktnummer ABIN7660158

Dieses Anti-SPTBN1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von SPTBN1 in WB und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SPTBN1 Antikörper (CF®594) (ABIN7660158)

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SPTBN1 Antikörper ist konjugiert mit CF®594

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: RG-26

Produktdetails anti-SPTBN1 Antikörper (CF®594)

Verwendungszweck: Spectrin beta I (SPTB)(RG/26), CF594 conjugate

Produktmerkmale: Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Red cell membranes

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: Jurkat whole cell lysate (WB). Human colon carcinoma tissue (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu SPTBN1

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Andere Bezeichnung: Spectrin beta I

Hintergrund:

Synonyms: beta-I spectrin, EL3, erythrocyte, HS2, SPTB1, HSPTB1, membrane cytoskeletal protein, spectrin beta (erythrocytic)

Gene Symbol: SPTB

Molekulargewicht: 246 kDa

Gen-ID: 6710

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Protein targeting to Nucleus