Rekombinanter RBP1 Antikörper (Biotin)

Produktnummer ABIN7659638

Der Maus Monoklonal Anti-RBP1-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, RBP1 in Proben von Human, Maus, Ratte, Kaninchen, Affe, Ziege und Schimpanse zu detektieren.

Kurzübersicht für Rekombinanter RBP1 Antikörper (Biotin) (ABIN7659638)

Target: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte, Kaninchen, Affe, Ziege, Schimpanse

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RBP1 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: RRBP1-872

Produktdetails anti-RBP1 Antikörper (Biotin)

Verwendungszweck: Retinol Binding Protein-1 (RBP1)(rRBP1/872), Biotin conjugate

Produktmerkmale: This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human RBP protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: Human Hepatic or Ovarian Carcinoma tissues (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu RBP1

Target: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Andere Bezeichnung: Retinol Binding Protein 1

Hintergrund:

Synonyms: Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma

Gene Symbol: RBP

Molekulargewicht: 21-25 kDa

Gen-ID: 5947, 5948, 5950

UniProt: P02753, P09455, P50120