Prolactin Receptor Antikörper (CF®740)

Produktnummer ABIN7659177

Dieses Anti-Prolactin Receptor-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Prolactin Receptor in IHC und IHC (fp). Geeignet für Human.

Kurzübersicht für Prolactin Receptor Antikörper (CF®740) (ABIN7659177)

Target: Prolactin Receptor (PRLR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prolactin Receptor Antikörper ist konjugiert mit CF®740

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: PRLR-742

Produktdetails anti-Prolactin Receptor Antikörper (CF®740)

Verwendungszweck: Prolactin Receptor(PRLR/742), CF740 conjugate

Produktmerkmale: This antibody recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human prolactin receptor

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology formalin-fixed 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

Kommentare:

Positive Control: Testicular Carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Andere Bezeichnung: Prolactin Receptor

Hintergrund:

Synonyms: CPRLP|hPRL receptor|hPRLrI|Lactogen receptor|OPR|Pr-1|Pr-3|PRL-R|Prolactin receptor delta 7/11|RATPRLR|Secreted prolactin binding protein|Truncated testis-specific box 1-C prolactin receptor

Gene Symbol: PRLR

Molekulargewicht: 70 kDa

Gen-ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus