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NAPSA Antikörper (AA 189-299) (CF®488A)

Dieses Anti-NAPSA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NAPSA in IHC und IHC (fp). Geeignet für Human.
Produktnummer ABIN7657728

Kurzübersicht für NAPSA Antikörper (AA 189-299) (CF®488A) (ABIN7657728)

Target

Alle NAPSA Antikörper anzeigen
NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Reaktivität

  • 143
  • 17
  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 81
  • 63
Maus

Klonalität

  • 98
  • 46
Monoklonal

Konjugat

  • 67
  • 12
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NAPSA Antikörper ist konjugiert mit CF®488A

Applikation

  • 95
  • 65
  • 61
  • 29
  • 17
  • 15
  • 12
  • 10
  • 9
  • 5
  • 3
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon

NAPSA-3306
  • Bindungsspezifität

    • 73
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 189-299

    Verwendungszweck

    Napsin A (Lung Adenocarcinoma Marker)(NAPSA/3306), CF488A conjugate

    Produktmerkmale

    Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogen

    Recombinant human Napsin-A protein fragment (aa189-299)

    Isotyp

    IgG1, kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Kommentare

    Positive Control: Lung adenocarcinoma

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from light

    Lagerung

    4 °C

    Informationen zur Lagerung

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Haltbarkeit

    24 months
  • Target

    NAPSA (Napsin A Aspartic Peptidase (NAPSA))

    Andere Bezeichnung

    Napsin-A

    Hintergrund

    Synonyms: ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA

    Gene Symbol: NAPSA

    Tissue Expression: Kidney|Lung

    Molekulargewicht

    37 kDa

    Gen-ID

    9476

    UniProt

    O96009

    Pathways

    Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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