IL7R Antikörper (AA 21-236) (CF®488A)

Produktnummer ABIN7655738

Der Maus Monoklonal Anti-IL7R-Antikörper wurde für WB validiert. Er ist geeignet, IL7R in Proben von Human zu detektieren.

Kurzübersicht für IL7R Antikörper (AA 21-236) (CF®488A) (ABIN7655738)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL7R Antikörper ist konjugiert mit CF®488A

Applikation: Western Blotting (WB)

Klon: IL7R-2751

Produktdetails anti-IL7R Antikörper (CF®488A)

Bindungsspezifität: AA 21-236

Verwendungszweck: CD127 / IL7R (Marker of T-Reg Cells)(IL7R/2751), CF488A conjugate

Produktmerkmale: The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R)

Isotyp: IgG2c, kappa

Anwendungsinformationen

Applikationshinweise: ELISA: For coating, order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Kommentare:

Positive Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Andere Bezeichnung: CD127

Hintergrund:

Synonyms: CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor

Gene Symbol: IL7R

Molekulargewicht: 52-72 kDa

Gen-ID: 3575

UniProt: P16871

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size