ICAM-3/CD50 Antikörper (Biotin)
Kurzübersicht für ICAM-3/CD50 Antikörper (Biotin) (ABIN7655578)
Target
Alle ICAM-3/CD50 (ICAM3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- CD50 / ICAM3(ICO-60), Biotin conjugate
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Produktmerkmale
- Recognizes the N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
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Immunogen
- Human ICAM3
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Flow cytometry: 0.5-1 μg/million cells. Immunofluorescence: 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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Kommentare
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Positive Control: HL-60 or THP-1 cells. Lymph node and tonsil
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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Andere Bezeichnung
- CD50
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Hintergrund
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Synonyms: ICAMR, Intercellular adhesion molecule 3 (ICAM3)
Gene Symbol: ICAM3
Tissue Expression: Lymphocytes|T-cells
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Molekulargewicht
- 110-160 kDa
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Gen-ID
- 3385
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UniProt
- P32942
Target
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