ITGB1 Antikörper (Biotin)

Produktnummer ABIN7655423

Der Maus Monoklonal Anti-ITGB1-Antikörper wurde für FACS, IP, IF und Func validiert. Er ist geeignet, ITGB1 in Proben von Human zu detektieren.

Kurzübersicht für ITGB1 Antikörper (Biotin) (ABIN7655423)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGB1 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func)

Klon: 12G10

Produktdetails anti-ITGB1 Antikörper (Biotin)

Verwendungszweck: CD29 (Stem Cell Marker)(12G10), Biotin conjugate

Produktmerkmale: Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Does not react with Mouse or Rat, ELISA: For coating use Ab at 1-5 μg/mL, order Ab without BSA, Optimal dilution for a specific application should be determined by user.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Kommentare:

Positive Control: HT1080 whole cell lysate. HeLa cell line.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Andere Bezeichnung: CD29

Hintergrund:

Synonyms: Fibrinogen Receptor beta subunit, FNRB, Glycoprotein IIa (GPIIA), Integrin beta-1 (ITGB1), integrin VLA-4 beta subunit, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLA-4 subunit beta, VLA-BETA, VLAB

Gene Symbol: ITGB1

Tissue Expression: Platelets|Endothelial cells|Fibroblasts|Lymphocytes|Mast cells|Monocytes/macrophages|Smooth muscle

Molekulargewicht: 110 kDa (non-reduced) & 130 kDa (reduced)

Gen-ID: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom