HNF1A Antikörper (AA 214-339) (Biotin)

Produktnummer ABIN7655150

Der Maus Monoklonal Anti-HNF1A-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, HNF1A in Proben von Human zu detektieren.

Kurzübersicht für HNF1A Antikörper (AA 214-339) (Biotin) (ABIN7655150)

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HNF1A Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: HNF1A-2087

Produktdetails anti-HNF1A Antikörper (Biotin)

Bindungsspezifität: AA 214-339

Verwendungszweck: HNF1A (Pancreatic Tumor Suppressor)(HNF1A/2087), Biotin conjugate

Produktmerkmale: HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1Aas a susceptibility gene for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 214-339) of human HNF1A protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: Jurkat cells. Small Intestine or Pancreas.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Andere Bezeichnung: HNF1A

Hintergrund:

Synonyms: Albumin proximal factor, Hepatic nuclear factor 1 alpha, Hepatic transcription factor 1 alpha, HNF-1A, Interferon production regulator factor, LFB1, LFB1 hepatic nuclear factor, Liver specific transcription factor LFB1, Maturity onset diabetes of the young 3 (MODY3), TCF1, Transcription factor 1 hepatic

Gene Symbol: HNF1A

Molekulargewicht: 79 kDa

Gen-ID: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis