Gastrin Antikörper

Produktnummer ABIN7654292

Der Maus Monoklonal Anti-Gastrin-Antikörper wurde für validiert. Er ist geeignet, Gastrin in Proben von Human zu detektieren.

Kurzübersicht für Gastrin Antikörper (ABIN7654292)

Target: Gastrin (GAST)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Gastrin Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Klon: GAST-2632

Produktdetails anti-Gastrin Antikörper

Verwendungszweck: Gastrin(GAST/2632)

Produktmerkmale: Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human GAST protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: Human Pituitary or Stomach.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu Gastrin

Target: Gastrin (GAST)

Andere Bezeichnung: Gastrin

Hintergrund:

Synonyms: Component II, GAS, Gast, Gastrin component I, Gastrin component II, Gastrin component III, Gastrin precursor, Gastrin-14, Gastrin-17, Gastrin-34, Gastrin-52, Gastrin-6, Gastrin-71

Gene Symbol: GAST

Tissue Expression: Pancreatic islet cells|Stomach

Molekulargewicht: 2/4/14 kDa

Gen-ID: 2520

UniProt: P01350