PSMA Antikörper (AA 232-433) (CF®488A)

Produktnummer ABIN7654156

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PSMA in . Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PSMA Antikörper (AA 232-433) (CF®488A) (ABIN7654156)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PSMA Antikörper ist konjugiert mit CF®488A

Applikation: Bitte anfragen

Klon: FOLH1-2121

Produktdetails anti-PSMA Antikörper (CF®488A)

Bindungsspezifität: AA 232-433

Verwendungszweck: FOLH1 / PSMA (Prostate Epithelial Marker)(FOLH1/2121), CF488A conjugate

Produktmerkmale: Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human FOLH1 protein fragment (around aa 232-433)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: LNCap or HepG2 cells. Prostate Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Andere Bezeichnung: FOLH1

Hintergrund:

Synonyms: Cell growth-inhibiting gene 27 protein (GIG27), Folylpoly-gamma-glutamate carboxypeptidase (FGCP), Glutamate carboxylase II (GCPII), N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1 or NAALADase), Prostate-specific membrane antigen (PSM or PSMA), Pteroylpoly-gamma-glutamate carboxypeptidase

Gene Symbol: FOLH1

Tissue Expression: Prostate

Molekulargewicht: 100 kDa

Gen-ID: 2346

UniProt: Q04609