Cathepsin K Antikörper (Biotin)

Produktnummer ABIN732040

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cathepsin K in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Cathepsin K Antikörper (Biotin) (ABIN732040)

Target: Cathepsin K (CTSK)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin K Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB)

Produktdetails anti-Cathepsin K Antikörper (Biotin)

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Capsin K

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:100-1000, IHC-P: 1:100-500
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Cathepsin K

Target: Cathepsin K (CTSK)

Andere Bezeichnung: Cathepsin K

Hintergrund:

Synonyms: Cathepsin K, Procathepsin K, Cathepsin K precursor, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CathepsinK, CTS02, CTSK, CTSK protein, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD, Pycnodysostosis, cath-K, CK.

Background: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq, Jul 2008].

Gen-ID: 1513

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades