Rekombinanter EPO Antikörper (AA 28-162) (CF®568)
Kurzübersicht für Rekombinanter EPO Antikörper (AA 28-162) (CF®568) (ABIN7653727)
Target
Alle EPO Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 28-162
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Verwendungszweck
- Erythropoietin (EPO) (Marker of Placentation Disorders)(EPO/3793R), CF568 conjugate
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Produktmerkmale
- Recognizes a protein of about 37 kDa, which is identified as Erythropoietin (EPO). Erythropoietin is a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. It is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. Erythropoietin is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant fragment (around aa 28-162) of human EPO protein
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Positive Control: HepG2 Cells. Heart or Kidney.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- EPO (Erythropoietin (EPO))
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Andere Bezeichnung
- Erythropoietin
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Substanzklasse
- Hormone
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Hintergrund
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Synonyms: EP, EPO alpha, EPO, Epoetin, Erythropoietin, MVCD2
Gene Symbol: EPO
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Molekulargewicht
- 37 kDa
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Gen-ID
- 2056
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UniProt
- P01588
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Pathways
- JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
Target
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