CD8B Antikörper (CF®488A)

Produktnummer ABIN7652222

Der Ratte Monoklonal Anti-CD8B-Antikörper wurde für FACS und Func validiert. Er ist geeignet, CD8B in Proben von Maus zu detektieren.

Kurzübersicht für CD8B Antikörper (CF®488A) (ABIN7652222)

Target: CD8B (CD8b Molecule (CD8B))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD8B Antikörper ist konjugiert mit CF®488A

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: H35-17-2

Produktdetails anti-CD8B Antikörper (CF®488A)

Verwendungszweck: CD8b, Mouse(H35-17.2), CF488A conjugate

Produktmerkmale: This rat monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: MPBMC or Thymus.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu CD8B

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: CD8b

Hintergrund:

Synonyms: CD8b antigen, CD8 antigen beta polypeptide 1 (p37), CD8 beta, CD8B1, Leu2, Ly3, LYT3, P37, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain

Gene Symbol: Cd8b1 (Mouse)

Tissue Expression: T-cells

Molekulargewicht: 37 kDa

Gen-ID: 12526

UniProt: P10300

Pathways: T-Zell Rezeptor Signalweg