CD8B Antikörper (CF®647)

Produktnummer ABIN7652215

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD8B in . Er zeigt eine Reaktivität gegenüber Rind (Kuh), Schaf und Ziege.

Kurzübersicht für CD8B Antikörper (CF®647) (ABIN7652215)

Target: CD8B (CD8b Molecule (CD8B))

Reaktivität: Rind (Kuh), Schaf, Ziege

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8B Antikörper ist konjugiert mit CF®647

Applikation: Bitte anfragen

Klon: CBB-1595

Produktdetails anti-CD8B Antikörper (CF®647)

Verwendungszweck: CD8B (Cytotoxic / Suppressor T-Cell Marker)(CBB/1595), CF647 conjugate

Produktmerkmale: The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Antibody was raised against bovine CD8b.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: HuT78 or hPBL. Tonsil

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu CD8B

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: CD8b

Hintergrund:

Synonyms: CD8 antigen 37 kDa chain, CD8 antigen, beta chain, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta polypeptide 1, CD8B, LEU2, LYT3, OX 8 membrane antigen, p37, T cell surface glycoprotein CD8 beta chain

Gene Symbol: CD8B

Tissue Expression: T-cells

Molekulargewicht: 32 kDa

Gen-ID: 926

UniProt: P10966

Pathways: T-Zell Rezeptor Signalweg