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CD79b Antikörper (AA 29-159) (CF®594)

Dieses Anti-CD79b-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD79b in WB. Geeignet für Human.
Produktnummer ABIN7652007

Kurzübersicht für CD79b Antikörper (AA 29-159) (CF®594) (ABIN7652007)

Target

Alle CD79b (CD79B) Antikörper anzeigen
CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reaktivität

  • 223
  • 59
  • 22
  • 8
  • 8
  • 2
  • 2
Human

Wirt

  • 124
  • 95
  • 15
  • 10
  • 6
  • 2
  • 2
  • 2
  • 1
Maus

Klonalität

  • 187
  • 62
  • 2
Monoklonal

Konjugat

  • 126
  • 19
  • 18
  • 16
  • 10
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD79b Antikörper ist konjugiert mit CF®594

Applikation

  • 104
  • 101
  • 94
  • 62
  • 39
  • 33
  • 30
  • 15
  • 11
  • 11
  • 8
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)

Klon

IGB-1843
  • Bindungsspezifität

    • 91
    • 13
    • 10
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-159

    Verwendungszweck

    CD79b (B-Cell Marker)(IGB/1843), CF594 conjugate

    Produktmerkmale

    CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogen

    Recombinant human CD79b protein fragment (around aa29-159)

    Isotyp

    IgG1, kappa
  • Applikationshinweise

    ELISA: Use Ab at 2-4 μg/mL for coating, Order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

    Kommentare

    Positive Control: Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from light

    Lagerung

    4 °C

    Informationen zur Lagerung

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Haltbarkeit

    24 months
  • Target

    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

    Andere Bezeichnung

    CD79b

    Hintergrund

    Synonyms: AGM6, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, B29/Ig-beta/CD79b, CD79b, Ig-beta, IGB, Immunoglobulin-associated B29 protein

    Gene Symbol: CD79B

    Tissue Expression: NK cells|T-cells

    Molekulargewicht

    39 kDa

    Gen-ID

    974

    UniProt

    P40259

    Pathways

    BCR Signaling
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