CD48 Antikörper (CF®740)
Kurzübersicht für CD48 Antikörper (CF®740) (ABIN7651650)
Target
Alle CD48 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- CD48(5-4.8), CF740 conjugate
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Produktmerkmale
- Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Human peripheral blood lymphocytes
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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Kommentare
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Positive Control: Daudi, JY, Raji, Jurkat, and human lymphocytes. Human lymph node and tonsil.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- CD48
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Andere Bezeichnung
- CD48
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Hintergrund
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Synonyms: B cell membrane protein, B-cell activation marker, BCM1 surface antigen, BLAST1, Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), TCT.1
Gene Symbol: CD48
Tissue Expression: Lymphocytes|Monocytes/macrophages
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Molekulargewicht
- 45 kDa
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Gen-ID
- 962
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UniProt
- P09326
Target
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