CD2 Antikörper (CF®488A)

Produktnummer ABIN7650943

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD2 in FACS, IF, IHC, Func und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD2 Antikörper (CF®488A) (ABIN7650943)

Target: CD2

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist konjugiert mit CF®488A

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Functional Studies (Func), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: UMCD2

Produktdetails anti-CD2 Antikörper (CF®488A)

Verwendungszweck: CD2 / Lymphocyte Function Antigen 2 (LFA-2)(UMCD2), CF488A conjugate

Produktmerkmale: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human Thymocytes/Sezary T cells

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Functional studies: Order Ab without azide, Flow cytometry: 0.5-1 μg/million cells, Immunofluorescence: 0.5-1 μg/mL, Optimal dilution for a specific application should be determined.

Kommentare:

Positive Control: 293T or Jurkat cells. Lymph node and tonsil

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund:

Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11

Gene Symbol: CD2

Tissue Expression: Lymphocytes|NK cells|T-cells

Molekulargewicht: ~50 kDa

Gen-ID: 914

UniProt: P06729