CTNND1 Antikörper (CF®740)

Produktnummer ABIN7650595

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CTNND1 in . Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für CTNND1 Antikörper (CF®740) (ABIN7650595)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTNND1 Antikörper ist konjugiert mit CF®740

Applikation: Bitte anfragen

Klon: 25a

Produktdetails anti-CTNND1 Antikörper (CF®740)

Verwendungszweck: Catenin, delta-1 (CTNND1) (pTyr96) (25a), CF740 conjugate

Produktmerkmale: Delta 1 catenin, also known as p120 catenin, is a tyrosine kinase substrate that is phosphorylated in Src transformed cells or in response to growth factor stimulation. Like beta- and gamma-catenin, p120 Catenin directly associates with the cytoplasmic C-terminus of E-Cadherin via its Arm domain and may similarly interact with other cadherins. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Mouse p120 Catenin (pY96)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Kommentare:

Positive Control: Carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Andere Bezeichnung: Catenin, Delta-1

Hintergrund:

Synonyms: Delta 1 cadherin, Catenin delta-1, Cadherin-associated Src substrate (CAS), Catenin (cadherin associated protein) delta 1, CTNND1, p120 catenin

Gene Symbol: CTNND1

Tissue Expression: Epithelial cells

Molekulargewicht: 120 kDa

Gen-ID: 1500

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling