BCL2L1 Antikörper (AA 1-135)
Kurzübersicht für BCL2L1 Antikörper (AA 1-135) (ABIN7650025)
Target
Alle BCL2L1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-135
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Verwendungszweck
- Bcl-X (Apoptosis Marker)(BCL2L1/1762)
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Produktmerkmale
- Bcl-x belongs to the Bcl-2 family of proteins and plays a crucial role in apoptosis. Bcl-X has two isoforms: Bcl-XL (long), a 26 kDa protein which suppresses cell death, and Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2 and promotes apoptosis. This MAb reacts with both Bcl-XS and Bcl-XL proteins, and shows no cross-reaction with Bcl-2 or Bax proteins.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant human BCL2L1 protein fragment (around aa 1-135)
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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Kommentare
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Positive Control: Jurkat, K562, HL-60, or HeLa Cells. Reed-Sternberg cells in Hodgkin's lymphoma.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, no BSA, no azide
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Konservierungsmittel
- Without preservative
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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Andere Bezeichnung
- Bcl-x
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Hintergrund
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Synonyms: Bcl-x, Bcl-2-like protein 1, BCL2L1, Apoptosis regulator Bcl-X
Gene Symbol: BCL2L1
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Molekulargewicht
- 27 kDa
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Gen-ID
- 598
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UniProt
- Q07817
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Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
Target
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