Liver Arginase Antikörper (AA 11-97)

Produktnummer ABIN7649681

Der Maus Monoklonal Anti-Liver Arginase-Antikörper wurde für IHC und IHC (fp) validiert. Er ist geeignet, Liver Arginase in Proben von Human zu detektieren.

Kurzübersicht für Liver Arginase Antikörper (AA 11-97) (ABIN7649681)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Liver Arginase Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: ARG1-1125 ARG1-1126

Produktdetails anti-Liver Arginase Antikörper

Bindungsspezifität: AA 11-97

Verwendungszweck: Arginase 1 (Hepatocellular Carcinoma Marker)(ARG1/1125+ ARG1/1126)

Produktmerkmale: This antibody recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibodies to Arginase 1 label hepatocytes in normal tissues and granulocytes in peripheral blood. Arginase 1 is a sensitive and specific marker for identification of hepatocellular carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human ARG1 protein fragment (around aa11-97)

Isotyp: IgG3, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: 293T cells. Hepatocellular Carcinoma (HCC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: Arginase 1

Hintergrund:

Synonyms: Arginase 1, ARG1, liver-type arginase, type I arginase

Gene Symbol: ARG1

Tissue Expression: Liver

Molekulargewicht: 35-38 kDa

Gen-ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin