APCS Antikörper (AA 143-223) (CF®405S)

Produktnummer ABIN7649434

Dieses Maus Monoklonal-Antikörper erkennt spezifisch APCS in IHC und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für APCS Antikörper (AA 143-223) (CF®405S) (ABIN7649434)

Target: APCS (Amyloid P Component, Serum (APCS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APCS Antikörper ist konjugiert mit CF®405S

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: APCS-3240

Produktdetails anti-APCS Antikörper (CF®405S)

Bindungsspezifität: AA 143-223

Verwendungszweck: Serum Amyloid P / APCS(APCS/3240), CF405S conjugate

Produktmerkmale: Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer's disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human APCS protein (around aa 143-223)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: Human endometrial carcinoma tissue (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Lagerung: 4 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu APCS

Target: APCS (Amyloid P Component, Serum (APCS))

Andere Bezeichnung: APCS

Hintergrund:

Synonyms: 9.5S alpha 1 glycoprotein, Amyloid P component serum (APCS), Pentaxin related, Pentraxin 2 (PTX2), Serum Amyloid P (SAP), Serum amyloid P component

Gene Symbol: APCS

Molekulargewicht: 200 kDa (oligomeric), 26 kDa (non-covalently bound subunit), 30 kDa (glycosylated SAP subunit)

Gen-ID: 325

UniProt: P02743