YWHAE Antikörper

Produktnummer ABIN7649012

Der Maus Monoklonal Anti-YWHAE-Antikörper wurde für WB, IHC und IHC (fp) validiert. Er ist geeignet, YWHAE in Proben von Human zu detektieren.

Kurzübersicht für YWHAE Antikörper (ABIN7649012)

Target: YWHAE (14-3-3 epsilon (YWHAE))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YWHAE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: CPTC-YWHAE-1

Produktdetails anti-YWHAE Antikörper

Verwendungszweck: 14-3-3E / Tryptophan 5-Monooxygenase(CPTC-YWHAE-1)

Produktmerkmale: 14-3-3E is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human full-length YWHAE protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Positive Control: HEK-293 or A-431 cell lines.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Haltbarkeit: 24 months

Details zu YWHAE

Target: YWHAE (14-3-3 epsilon (YWHAE))

Andere Bezeichnung: 14-3-3E

Hintergrund:

Synonyms: YWHAE, Tyrosine 3-Monooxygenase Activation Protein Epsilon, Tryptophan 5-Monooxygenase Activation Protein Epsilon, epididymis luminal protein 2, Mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1

Gene Symbol: YWHAE

Molekulargewicht: 29.4 kDa

Gen-ID: 7531

UniProt: P62268

Pathways: Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, M Phase