SLC16A1 Antikörper (C-Term)

Produktnummer ABIN731468

Der Kaninchen Polyklonal Anti-SLC16A1-Antikörper wurde für IF (p) und IHC (p) validiert. Er ist geeignet, SLC16A1 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Schwein und Huhn zu detektieren.

Kurzübersicht für SLC16A1 Antikörper (C-Term) (ABIN731468)

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Schwein, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC16A1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SLC16A1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Huhn, Rind (Kuh), Hund, Human, Maus, Schwein, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P (1:100-500), FACS (1:50-200), IF (p) (1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SLC16A1

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Andere Bezeichnung: MCT1

Hintergrund:

Synonyms: Monocarboxylate transporter 1, MCT 1, Solute carrier family 16 member 1, SLC16A1, MCT1

Background: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

Molekulargewicht: 55kDa

Gen-ID: 6566

Pathways: Warburg Effekt