RAMP1 Antikörper (AA 118-148)

Produktnummer ABIN731438

Der Kaninchen Polyklonal Anti-RAMP1-Antikörper wurde für ELISA, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, RAMP1 in Proben von Human und Ratte zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für RAMP1 Antikörper (AA 118-148) (ABIN731438)

Target: RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAMP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RAMP1 Antikörper

Bindungsspezifität: AA 118-148

Kreuzreaktivität: Human, Ratte

Homologie: Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse RAMP-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-RAMP1 Antikörper (ABIN731438)

Zheng, Nixdorf-Bergweiler, van Brederode, Alzheimer, Messlinger: "Excitatory Effects of Calcitonin Gene-Related Peptide (CGRP) on Superficial Sp5C Neurons in Mouse Medullary Slices." in: International journal of molecular sciences, Vol. 22, Issue 7, (2021) (PubMed).

Ragauskas, Rysevaite-Kyguoliene, Pauziene, Inokaitis, Pauza: "Chemical phenotypes of intrinsic cardiac neurons in the newborn pig (Sus scrofa domesticus Erxleben, 1777)." in: Journal of morphology, Vol. 283, Issue 1, pp. 51-65, (2021) (PubMed).

Pauza, Rysevaite-Kyguoliene, Malinauskas, Lukosiene, Alaburda, Stankevicius, Kupcinskas, Saladzinskas, Tamelis, Pauziene: "Alterations in enteric calcitonin gene-related peptide in patients with colonic diverticular disease: CGRP in diverticular disease." in: Autonomic neuroscience : basic & clinical, Vol. 216, pp. 63-71, (2019) (PubMed).

Qiao, Wang, Wang, Zhao, Zhang, Han, Peng: "Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction." in: Nephrology (Carlton, Vic.), (2015) (PubMed).

Details zu RAMP1

Target: RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))

Andere Bezeichnung: RAMP1

Hintergrund:

Synonyms: 9130218E19Rik, Receptor activity-modifying protein 1, Ramp1

Background: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.

Gen-ID: 51801

UniProt: Q9WTJ5

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process