RAMP1 Antikörper (AA 118-148)

Produktnummer ABIN731438

Es sind 4+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-RAMP1 Antikörper wird verwendet zum Nachweis von RAMP1 in Proben von Human und Ratte. Er wurde validiert für ELISA, IF (cc), IF (p), IHC (fro) und IHC (p).

Kurzübersicht für RAMP1 Antikörper (AA 118-148) (ABIN731438)

Target: RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAMP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RAMP1 Antikörper

Bindungsspezifität: AA 118-148

Kreuzreaktivität: Human, Ratte

Homologie: Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse RAMP-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-RAMP1 Antikörper (ABIN731438)

Zheng, Nixdorf-Bergweiler, van Brederode, Alzheimer, Messlinger: "Excitatory Effects of Calcitonin Gene-Related Peptide (CGRP) on Superficial Sp5C Neurons in Mouse Medullary Slices." in: International journal of molecular sciences, Vol. 22, Issue 7, (2021) (PubMed).

Ragauskas, Rysevaite-Kyguoliene, Pauziene, Inokaitis, Pauza: "Chemical phenotypes of intrinsic cardiac neurons in the newborn pig (Sus scrofa domesticus Erxleben, 1777)." in: Journal of morphology, Vol. 283, Issue 1, pp. 51-65, (2021) (PubMed).

Pauza, Rysevaite-Kyguoliene, Malinauskas, Lukosiene, Alaburda, Stankevicius, Kupcinskas, Saladzinskas, Tamelis, Pauziene: "Alterations in enteric calcitonin gene-related peptide in patients with colonic diverticular disease: CGRP in diverticular disease." in: Autonomic neuroscience : basic & clinical, Vol. 216, pp. 63-71, (2019) (PubMed).

Qiao, Wang, Wang, Zhao, Zhang, Han, Peng: "Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction." in: Nephrology (Carlton, Vic.), (2015) (PubMed).

Details zu RAMP1

Target: RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))

Andere Bezeichnung: RAMP1

Hintergrund:

Synonyms: 9130218E19Rik, Receptor activity-modifying protein 1, Ramp1

Background: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.

Gen-ID: 51801

UniProt: Q9WTJ5

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process