Reelin Antikörper

Produktnummer ABIN731348

Produktdetails anti-Reelin Antikörper

Target: Reelin (RELN)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Reelin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RELN

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C

Haltbarkeit: 12 months

Details zu Reelin

Target: Reelin (RELN)

Andere Bezeichnung: Reln/Reelin (RELN Produkte)

Hintergrund:

Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).

Subcellular location: Extracellular, Secreted

Synonyms: RL, ETL7, LIS2, PRO1598, Reelin, RELN

Gen-ID: 5649

UniProt: P78509

Pathways: Synaptic Membrane