Melatonin Receptor 1B Antikörper (AA 201-300)

Produktnummer ABIN730318

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Melatonin Receptor 1B in ELISA, WB, IHC (p), IHC (fro), IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Ziege und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Melatonin Receptor 1B Antikörper (AA 201-300) (ABIN730318)

Target: Melatonin Receptor 1B (MTNR1B)

Reaktivität: Human, Maus, Ratte, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melatonin Receptor 1B Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Melatonin Receptor 1B Antikörper

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Ziege, Human, Maus, Ratte

Homologie: Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MTNR1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Melatonin Receptor 1B Antikörper (ABIN730318)

Jang, Na, Hong, Lee, Moon, Cho, Park, Lee, Chang, Lee, Ko, Lee, Choi: "Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1promoter in primordial follicles." in: Journal of pineal research, Vol. 63, Issue 3, (2017) (PubMed).

Brockus, Hart, Gilfeather, Fleming, Lemley: "Dietary melatonin alters uterine artery hemodynamics in pregnant Holstein heifers." in: Domestic animal endocrinology, Vol. 55, pp. 1-10, (2016) (PubMed).

Wang, Liu, Wu, Ma, Ahmad, Liu, Han, Jiang, Zhang, Yang: "Melatonin suppresses apoptosis and stimulates progesterone production by bovine granulosa cells via its receptors (MT1 and MT2)." in: Theriogenology, Vol. 78, Issue 7, pp. 1517-26, (2012) (PubMed).

Details zu Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Andere Bezeichnung: MTNR1B

Hintergrund:

Synonyms: MT2, FGQTL2, MEL-1B-R, Melatonin receptor type 1B, Mel1b receptor, MTNR1B

Background: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Gen-ID: 4544

UniProt: P49286