Melatonin Receptor 1B Antikörper (N-Term)

Produktnummer ABIN2789720

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Melatonin Receptor 1B in WB. Es zeigt Reaktivität gegenüber Proben von Human, Schwein und Kaninchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für Melatonin Receptor 1B Antikörper (N-Term) (ABIN2789720)

Target: Melatonin Receptor 1B (MTNR1B)

Reaktivität: Human, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melatonin Receptor 1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Melatonin Receptor 1B Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MTNR1B Antibody - N-terminal region

Sequenz: SFANCCEAGG WAVRPGWSGA GSARPSRTPR PPWVAPALSA VLIVTTAVDV

Homologie: Human: 100%, Pig: 79%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MTNR1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64072-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Melatonin Receptor 1B Antikörper (ABIN2789720)

Santoro, Mori, Marani, Grasso, Cambria, Blandino, Muti, Strano: "Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation." in: Carcinogenesis, Vol. 34, Issue 5, pp. 1051-61, (2013) (PubMed).

Details zu Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Andere Bezeichnung: MTNR1B

Hintergrund:

Background Information: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.

Gene Name: Melatonin receptor 1B

Alternative Symbols: MT2, FGQTL2, MEL-1B-R

Protein Name: Melatonin receptor type 1B

Molekulargewicht: 40 kDa

Gen-ID: 4544

NCBI Accession: NP_005950

UniProt: P49286