AKT 1/2/3 Antikörper (pSer473) (PE)
Kurzübersicht für AKT 1/2/3 Antikörper (pSer473) (PE) (ABIN729308)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer473
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Kreuzreaktivität
- Huhn, Rind (Kuh), Fisch, Human, Maus, Kaninchen, Ratte
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Homologie
- Dog,Cow,Sheep
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human AKT1 around the phosphorylation site of Ser473
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Isotyp
- IgG
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anti-AKT 1/2/3 (AA 401-479) antibody
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pSer473) antibodyReaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Huhn, Fisch WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pSer472) antibodyReaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReaktivität: Human, Maus, Ratte, Schimpanse WB, IHC, FACS, ELISA Wirt: Maus Monoclonal 14E5-16C8-25F6 unconjugated
anti-AKT 1/2/3 (pTyr474) antibodyReaktivität: Human, Maus WB, FACS, IF (cc), IF (p), ELISA, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pThr305), (pThr308), (pThr309) antibodyReaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB3180 unconjugated Recombinant Antibody
anti-AKT 1/2/3 antibodyReaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB3185 unconjugated Recombinant Antibody
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Applikationshinweise
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FCM: 1:20-100
Optimal working dilution should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- AKT 1/2/3
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Andere Bezeichnung
- AKT1/2/3
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Hintergrund
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Synonyms: Akt, RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, RAC-PK-alpha, Akt1
Background: AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility, prohibitin (PHB), playing an important role in cell metabolism and proliferation, and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
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Gen-ID
- 24185
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UniProt
- P47196
Target
-
