MICA Antikörper (AA 120-170)
Kurzübersicht für MICA Antikörper (AA 120-170) (ABIN728788)
Target
Alle MICA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 120-170
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human MICA
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Isotyp
- IgG
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Applikationshinweise
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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Scorpion venom activates natural killer cells in hepatocellular carcinoma via the NKG2D-MICA pathway." in: International immunopharmacology, Vol. 35, pp. 307-14, (2016) (PubMed).
: "
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Scorpion venom activates natural killer cells in hepatocellular carcinoma via the NKG2D-MICA pathway." in: International immunopharmacology, Vol. 35, pp. 307-14, (2016) (PubMed).
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Andere Bezeichnung
- MICA
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Hintergrund
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Synonyms: MIC-A, PERB11.1, MHC class I polypeptide-related sequence A, MICA
Background: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
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Gen-ID
- 100507436
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UniProt
- Q29983
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Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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