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Angiopoietin 1 Antikörper (AA 276-375)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Angiopoietin 1 in WB, ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 5+ Publikationen erwähnt.
Produktnummer ABIN728323

Kurzübersicht für Angiopoietin 1 Antikörper (AA 276-375) (ABIN728323)

Target

Alle Angiopoietin 1 (ANGPT1) Antikörper anzeigen
Angiopoietin 1 (ANGPT1)

Reaktivität

  • 110
  • 34
  • 33
  • 13
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 119
  • 19
  • 1
  • 1
Kaninchen

Klonalität

  • 102
  • 38
Polyklonal

Konjugat

  • 77
  • 19
  • 10
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Angiopoietin 1 Antikörper ist unkonjugiert

Applikation

  • 105
  • 56
  • 33
  • 33
  • 25
  • 15
  • 12
  • 12
  • 8
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 276-375

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Dog,Cow,Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from mouse Angiopoietin 1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Xiang, Hu, Shen, Liu, Hua, Zan, Zu, Cui, Ye: "Bone marrow mesenchymal stem cells-conditioned medium enhances vascular remodeling after stroke in type 2 diabetic rats." in: Neuroscience letters, Vol. 644, pp. 62-66, (2017) (PubMed).

    Zhou, Deng, Hu, Wang, Chen, Cui, Cao, Song: "Ultrasound combined with targeted cationic microbubble-mediated angiogenesis gene transfection improves ischemic heart function." in: Experimental and therapeutic medicine, Vol. 13, Issue 5, pp. 2293-2303, (2017) (PubMed).

    He, Qi, Jia, Wang, Wang, Song, Fu, Li, Luo: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." in: Cancer letters, Vol. 368, Issue 1, pp. 115-25, (2015) (PubMed).

    Zhao, Hu, Xiang, Gu, Jin, Hua, Zhang, Liu, Zan, Zhang, Zu, Yang, Shi, Zhu, Xu, Cui, Ye: "Intranasal administration of human umbilical cord mesenchymal stem cells-conditioned medium enhances vascular remodeling after stroke." in: Brain research, (2015) (PubMed).

    Lv, Fan, Su: "Is a swine model of arteriovenous malformation suitable for human extracranial arteriovenous malformation? A preliminary study." in: Cardiovascular and interventional radiology, Vol. 36, Issue 5, pp. 1364-70, (2013) (PubMed).

  • Target

    Angiopoietin 1 (ANGPT1)

    Andere Bezeichnung

    Angiopoietin 1

    Hintergrund

    Synonyms: AGP 1, AGP1, AGPT, ANG 1, ANG1, Angiopoietin1, Angiogenin, ANGPT 1, ANGPT1, ANGPT-1, Angiopoietin-1, Angiopoietin 1, ANG-1, angiopoietin-1 isoform 1 precursor, ANGP1_HUMAN.

    Background: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].

    Gen-ID

    11600

    Pathways

    RTK Signalweg, Glycosaminoglycan Metabolic Process
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