FGL2 Antikörper (AA 75-150)

Produktnummer ABIN727785

Dieses Anti-FGL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FGL2 in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für FGL2 Antikörper (AA 75-150) (ABIN727785)

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-FGL2 Antikörper

Bindungsspezifität: AA 75-150

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat FGL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-FGL2 Antikörper (ABIN727785)

Yang, Fujikado, Kolodin, Benoist, Mathis: "Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance." in: Science (New York, N.Y.), Vol. 348, Issue 6234, pp. 589-94, (2015) (PubMed).

Details zu FGL2

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Andere Bezeichnung: FGL2

Hintergrund:

Synonyms: Fibroleukin, Cytotoxic T-lymphocyte-specic protein, Fibrinogen-like protein 2, Fibrinogen like protein 2, Prothrombinase, Fibroleukin, pT49, T49, G3V7P2_RAT, Fibrinogen-like 2.

Background: FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.

Gen-ID: 84586

UniProt: G3V7P2