FGL2 Antikörper (AA 75-150)

Produktnummer ABIN727785

Dieser Anti-FGL2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FGL2 in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für FGL2 Antikörper (AA 75-150) (ABIN727785)

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-FGL2 Antikörper

Bindungsspezifität: AA 75-150

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat FGL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-FGL2 Antikörper (ABIN727785)

Yang, Fujikado, Kolodin, Benoist, Mathis: "Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance." in: Science (New York, N.Y.), Vol. 348, Issue 6234, pp. 589-94, (2015) (PubMed).

Details zu FGL2

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Andere Bezeichnung: FGL2

Hintergrund:

Synonyms: Fibroleukin, Cytotoxic T-lymphocyte-specic protein, Fibrinogen-like protein 2, Fibrinogen like protein 2, Prothrombinase, Fibroleukin, pT49, T49, G3V7P2_RAT, Fibrinogen-like 2.

Background: FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.

Gen-ID: 84586

UniProt: G3V7P2