FGL2 Antikörper (Middle Region)

Produktnummer ABIN2784837

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FGL2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen und Kaninchen. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für FGL2 Antikörper (Middle Region) (ABIN2784837)

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGL2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: FGL2 Antibody - middle region

Sequenz: WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FGL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52235-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FGL2 Antikörper (ABIN2784837)

Pischke, Gustavsen, Orrem, Egge, Courivaud, Fontenelle, Despont, Bongoni, Rieben, Tønnessen, Nunn, Scott, Skulstad, Barratt-Due, Mollnes: "Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function." in: Basic research in cardiology, Vol. 112, Issue 3, pp. 20, (2017) (PubMed).

Bongoni, Klymiuk, Wolf, Ayares, Rieben, Cowan: "Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation." in: Transplantation, Vol. 100, Issue 9, pp. 1871-9, (2016) (PubMed).

Details zu FGL2

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Andere Bezeichnung: FGL2

Hintergrund:

Background Information: The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.

Gene Name: Fibrinogen-like 2

Alternative Symbols: T49, pT49

Protein Name: Fibroleukin

Molekulargewicht: 50 kDa

Gen-ID: 10875

NCBI Accession: NP_006673

UniProt: Q14314