Rekombinanter Thymic Stromal Lymphopoietin Antikörper (Biotin)

Produktnummer ABIN7608398

Der Human Chimeric anti-Thymic Stromal Lymphopoietin Antikörper wird verwendet zum Nachweis von Thymic Stromal Lymphopoietin in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Rekombinanter Thymic Stromal Lymphopoietin Antikörper (Biotin) (ABIN7608398)

Target: Thymic Stromal Lymphopoietin (TSLP)

Antikörpertyp: Recombinant Antibody

Fragment: Fc fragment

Reaktivität: Human

Wirt: Human, Kaninchen

Klonalität: Chimeric

Konjugat: Dieser Thymic Stromal Lymphopoietin Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: DMC426

Produktdetails anti-Thymic Stromal Lymphopoietin Antikörper (Biotin)

Verwendungszweck: Biotinylated Anti-TSLP antibody(DMC426), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Andere Bezeichnung: TSLP

Hintergrund: This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c( ) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.

UniProt: Q969D9