IL-13 Antikörper (Biotin)
Kurzübersicht für IL-13 Antikörper (Biotin) (ABIN7608275)
Target
Alle IL-13 (IL13) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Biotinylated Anti-IL13 antibody(1A1), IgG1 Chimeric mAb
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Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
- ELISA 1/5000-10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Haltbarkeit
- 12 months
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- IL-13 (IL13) (Interleukin 13 (IL13))
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Andere Bezeichnung
- IL13
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Hintergrund
- This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
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UniProt
- P35225
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Pathways
- JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
Target
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