Rekombinanter FGFR4 Antikörper (Biotin)

Produktnummer ABIN7851713

Der Biotin-konjugierte Human Chimeric anti-FGFR4 Antikörper (Klon DMC460) (ABIN7851713) detektiert spezifisch FGFR4 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter FGFR4 Antikörper (Biotin) (ABIN7851713)

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Antikörpertyp: Recombinant Antibody

Fragment: Fc fragment

Reaktivität: Human

Wirt: Human, Kaninchen

Klonalität: Chimeric

Konjugat: Dieser FGFR4 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: DMC460

Produktdetails anti-FGFR4 Antikörper (Biotin)

Verwendungszweck: Biotinylated Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu FGFR4

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Andere Bezeichnung: FGFR4

Hintergrund: The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]

UniProt: P22455

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding