Amphiregulin Antikörper

Produktnummer ABIN7607947

Dieses Human Chimeric-Antikörper erkennt spezifisch Amphiregulin in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Amphiregulin Antikörper (ABIN7607947)

Target: Amphiregulin (AREG)

Reaktivität: Human

Wirt: Human, Kaninchen

Klonalität: Chimeric

Konjugat: Dieser Amphiregulin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 1B12

Produktdetails anti-Amphiregulin Antikörper

Verwendungszweck: Anti-AREG antibody(1B12), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu Amphiregulin

Target: Amphiregulin (AREG)

Andere Bezeichnung: AREG

Hintergrund: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]

UniProt: P15514

Pathways: RTK Signalweg, EGFR Signaling Pathway