TRF2 Antikörper

Produktnummer ABIN7606575

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch TRF2 in WB, IHC, ICC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRF2 Antikörper (ABIN7606575)

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: AFOB-20

Produktdetails anti-TRF2 Antikörper

Verwendungszweck: Anti-TRF2 Monoclonal Antibody

Produktmerkmale: Anti-TRF2 Monoclonal Antibody (ABIN7606575). Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human TRF2 Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Andere Bezeichnung: TERF2

Hintergrund:

Synonyms: DNA-dependent protein kinase catalytic subunit,DNA-PK catalytic subunit,DNA-PKcs,2.7.11.1,DNPK1,p460,PRKDC,HYRC, HYRC1,

Tissue Specificity: Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells.

Molekulargewicht: 42 kDa

UniProt: Q15554

Pathways: Zellzyklus, Telomere Maintenance