FAP Antikörper

Produktnummer ABIN7604820

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch FAP in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für FAP Antikörper (ABIN7604820)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: AbF22

Produktdetails anti-FAP Antikörper

Verwendungszweck: Anti-FAP1 Rabbit Monoclonal Antibody

Produktmerkmale: Anti-FAP1 Rabbit Monoclonal Antibody (ABIN7604820). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human FAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Andere Bezeichnung: FAP

Hintergrund:

Synonyms: Prolyl endopeptidase FAP ,3.4.21.26 ,170 kDa melanoma membrane-bound gelatinase ,Dipeptidyl peptidase FAP ,3.4.14.5 ,Fibroblast activation protein alpha ,FAPalpha ,Gelatine degradation protease FAP ,3.4.21.- ,Integral membrane serine protease ,Post-proline cleaving enzyme ,Serine integral membrane protease ,SIMP ,Surface-expressed protease ,Seprase ,Antiplasmin-cleaving enzyme FAP, soluble form ,APCE ,3.4.14.5 ,3.4.21.- ,3.4.21.26 ,FAP ,

Tissue Specificity: Expressed in adipose tissue. Expressed in the dermal fibroblasts in the fetal skin. Expressed in the granulation tissue of healing wounds and on reactive stromal fibroblast in epithelial cancers. Expressed in activated fibroblast-like synoviocytes from inflamed synovial tissues. Expressed in activated hepatic stellate cells (HSC) and myofibroblasts from cirrhotic liver, but not detected in normal liver. Expressed in glioma cells (at protein level). Expressed in glioblastomas and glioma cells. Isoform 1 and isoform 2 are expressed in melanoma, carcinoma and fibroblast cell lines. .

Molekulargewicht: 95 kDa

UniProt: Q12884

Pathways: Tube Formation